Effect of feed enzymes and functional immunostimulants supplementation on growth performance and overall health of postlarvae and juvenile Pacific white shrimp, <i>Penaeus vannamei</i>, fed soybean‐based diets

Soybean meal (SBM) is widely used in shrimp feed agro-industry as a fish (FM) replacement. However, high levels of SBM may compromise animal health result nutrient imbalance. This study aimed to investigate the effects enzyme combination (a mixture 6-phytase, serine protease, and endo-1,3(4)-β-glucanase) functional immunostimulant brewer's yeast, nucleotides, vitamin C, E) improving overall Pacific white fed soybean-based diet. Four diets were formulated with different amounts SBM, FM, poultry (PM): 0% (with 25% FM 12.6% PM), 30% 12.5% 5.7% plus 0.045% enzymes, 0.1% immunostimulants. The postlarvae test for 45 days. Then, body weight, survival, FCR, Vibrio spp. count, immune responses analyzed. resistance parahaemolyticus infection was also evaluated. results suggest that diet deleterious shrimp's health. Feed enzymes supplements improved performance, function, V. containing compared without supplements.